Open Date September 25 - All times are ET.
at Louisville
Atlanta, GA
Louisville
Saturday, September 6
8:00 pm     ESPN
This is the first meeting between Ole Miss and the Cardinals.
43-24 (W)
vs Austin Peay
Oxford, MS
Austin Peay
Saturday, September 11
7:30 pm     ESPN+
54-17 (W)
vs Tulane
Oxford, MS
Tulane
Saturday, September 18
8:00 pm     ESPN2
The last time these two teams played was September 22, 2012. Ole Miss won the game 39-0.
61-21 (W)
at Alabama
Tuscaloosa, AL
Alabama
Saturday, October 2
3:30 pm     CBS
The last time these two teams played was October 10, 2020. Ole Miss lost the game 63-48.
42-21 (L)
vs Arkansas
Oxford, MS
Arkansas
Saturday, October 9
12:00 pm     ESPN
The last time these two teams played was October 17, 2020. Ole Miss lost the game 33-21.
52-51 (W)
at Tennessee
Knoxville, TN
Tennessee
Saturday, October 16
7:30 pm     SECN
The last time these two teams played was October 18, 2014. Ole Miss won the game 34-3.
31-26 (W)
vs LSU
Oxford, MS
LSU
Saturday, October 23
3:30 pm     CBS
The last time these two teams played was December 20, 2020. Ole Miss lost the game 53-48.
31-17 (W)
at Auburn
Auburn, AL
Auburn
Saturday, October 30
7:00 pm     ESPN
The last time these two teams played was October 24, 2020. Ole Miss lost the game 35-28.
31-20 (L)
vs Liberty
Oxford, MS
Liberty
Saturday, November 6
12:00 pm     SECN
27-14 (W)
vs Texas A&M
Oxford, MS
Texas A&M
Saturday, November 13
7:00 pm     ESPN
The last time these two teams played was October 19, 2019. Ole Miss lost the game 24-17.
29-19 (W)
vs Vanderbilt
Oxford, MS
Vanderbilt
Saturday, November 20
7:30 pm     SECN
The last time these two teams played was October 31, 2020. Ole Miss won the game 54-21.
31-17 (W)
at Mississippi State
Starkville, MS
Mississippi State
Thursday, November 25
7:30 pm     ESPN
The last time these two teams played was November 28, 2020. Ole Miss won the game 31-24.
31-21 (W)