Open Date October 23 - All times are ET.
vs Central Michigan
Columbia, MO
Central Michigan
Saturday, September 4
4:00 pm     SECN
This is the first meeting between The Tigers and the Chippewas.
34-24 (W)
at Kentucky
Lexington, KY
Kentucky
Saturday, September 11
7:30 pm     SECN
The last time these two teams played was October 24, 2020. The Tigers won the game 20-10.
35-28 (L)
vs SE Missouri State
Columbia, MO
SE Missouri State
Saturday, September 18
12:00 pm     ESPN+
59-28 (W)
at Boston College
Chestnut Hill, MA
Boston College
Saturday, September 25
12:00 pm     ESPN2
This is the first meeting between The Tigers and the Eagles.
41-34 (L)
vs Tennessee
Columbia, MO
Tennessee
Saturday, October 2
12:00 pm     SECN
The last time these two teams played was October 3, 2020. The Tigers lost the game 35-12.
62-24 (L)
vs North Texas
Columbia, MO
North Texas
Saturday, October 9
4:00 pm     SECN
The last time these two teams played was September 2, 1995. The Tigers won the game 28-7.
48-35 (W)
vs Texas A&M
Columbia, MO
Texas A&M
Saturday, October 16
12:00 pm     SECN
The last time these two teams played was November 15, 2014. The Tigers won the game 34-27.
35-14 (L)
at Vanderbilt
Nashville, TN
Vanderbilt
Saturday, October 30
3:00 pm     SECN
The last time these two teams played was November 28, 2020. The Tigers won the game 41-0.
37-28 (W)
at Georgia
Athens, GA
Georgia
Saturday, November 6
12:00 pm     ESPN
The last time these two teams played was December 12, 2020. The Tigers lost the game 49-14.
43-6 (L)
vs South Carolina
Columbia, MO
South Carolina
Saturday, November 13
4:00 pm     SECN
The last time these two teams played was November 21, 2020. The Tigers won the game 17-10.
31-28 (W)
vs Florida
Columbia, MO
Florida
Saturday, November 20
4:00 pm     SECN
The last time these two teams played was October 31, 2020. The Tigers lost the game 41-17.
24-23 (L)
vs Arkansas
Columbia, MO
Arkansas
Friday, November 26
3:30 pm     CBS
The last time these two teams played was December 5, 2020. The Tigers won the game 50-48.
34-17 (L)